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Tbio
IGLL5
Immunoglobulin lambda-like polypeptide 5

Protein Summary
Description
This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000526893
  • ENSP00000431254
  • ENSG00000254709
  • ENST00000531372
  • ENSP00000434368

Symbol
  • IGL
  • IGLV
  • VL-MAR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease
0.85
tissue
0.65
protein domain
0.58
cell line
0.46
cellular component
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 242.38   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 242.38   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (12)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (176)
1 – 10 of 176
IGLC2
Tdark
p_int: 1
Data Source: BioPlex
IGLC3
Tdark
p_int: 1
Data Source: BioPlex
IGLC7
Tdark
p_int: 0.99999994
p_ni: 5.9e-8
p_wrong: 1e-9
Data Source: BioPlex
DDX31
Tbio
Family: Enzyme
Novelty: 2.84646195
p_int: 0.999997574
p_ni: 6.8e-8
p_wrong: 0.000002358
Data Source: BioPlex
IGLL1
Tbio
Novelty: 0.0032269
p_int: 0.999969936
p_ni: 1.7e-8
p_wrong: 0.000030047
Score: 0.932
Data Source: BioPlex,STRINGDB
TRIM68
Tbio
Family: Enzyme
Novelty: 0.11729189
p_int: 0.998944918
p_ni: 0.001055081
p_wrong: 2e-9
Data Source: BioPlex
FRMD1
Tdark
Novelty: 0.96833141
p_int: 0.996628672
p_ni: 0.003302977
p_wrong: 0.000068351
Score: 0.211
Data Source: BioPlex,STRINGDB
TSPAN11
Tdark
Novelty: 0.37247094
p_int: 0.968702038
p_ni: 0.029635891
p_wrong: 0.001662071
Score: 0.177
Data Source: BioPlex,STRINGDB
ULBP1
Tbio
Novelty: 0.01603533
p_int: 0.964542636
p_ni: 0.030424959
p_wrong: 0.005032406
Score: 0.189
Data Source: BioPlex,STRINGDB
CA8
Tbio
Family: Enzyme
Novelty: 0.0041859
p_int: 0.964077358
p_ni: 0.00216023
p_wrong: 0.033762412
Data Source: BioPlex
Publication Statistics
PubMed Score  242.38

PubMed score by year
PubTator Score  2.19

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer