Tdark KIF28P Kinesin-like protein KIF28P

Protein Summary

Description

Microtubule-dependent motor protein required for mitochondrion morhology and transport of mitochondria in neuronal cells.

Uniprot Accession IDs

• B7ZC32

Gene Name

• KIF28P

Symbol

• KLP6
• KLP-6

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.84
cell type or tissue	0.67
gene perturbation	0.62
PubMedID	0.35
trait	0.3

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kif28p

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kif28p

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 0   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0