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Tbio
B7ZAP0
Rab GTPase-activating protein 1-like, isoform 10

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367688
  • ENSP00000356661
  • ENSG00000152061

Symbol
  • HHL
  • KIAA0471
  • HHL
  • TBC1D18
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.57   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.57   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
SYCE1
Tbio
Novelty:  0.05038876
p_int:  0.999999872
p_ni:  1.29e-7
Data Source:  BioPlex
SGF29
Tbio
Family:  Epigenetic
Novelty:  0.0426456
p_int:  0.999997807
p_ni:  0.000002193
Data Source:  BioPlex
PXDC1
Tdark
Novelty:  0.82453616
p_int:  0.999993865
p_ni:  6e-8
p_wrong:  0.000006075
Score:  0.19
Data Source:  BioPlex,STRINGDB
TRIM11
Tbio
Family:  Enzyme
Novelty:  0.02243955
p_int:  0.999983982
p_ni:  0.000016018
Data Source:  BioPlex
HOXC4
Tbio
Family:  TF
Novelty:  0.02206351
p_int:  0.999983216
p_ni:  0.000016784
Score:  0.216
Data Source:  BioPlex,STRINGDB
CORO1A
Tbio
Novelty:  0.00898925
p_int:  0.999956616
p_ni:  0.000043384
Score:  0.166
Data Source:  BioPlex,STRINGDB
EXOC1
Tbio
Novelty:  0.01073858
p_int:  0.999956149
p_ni:  0.000043851
Score:  0.169
Data Source:  BioPlex,STRINGDB
VIPR2
Tchem
Family:  GPCR
Novelty:  0.00463802
p_int:  0.999874422
p_ni:  0.000125578
Data Source:  BioPlex
DLK2
Tbio
Novelty:  0.06366405
p_int:  0.999485219
p_ni:  0.00051478
Data Source:  BioPlex
RFTN2
Tdark
Novelty:  0.99330616
p_int:  0.999248852
p_ni:  0.000751147
Score:  0.158
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (56)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
3
6
74.6
neutrophil count
2
3
6
74.6
body mass index
3
3
6
71.4
body mass index
3
3
6
71.4
daytime rest measurement
1
1
2
70.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
6
74.6
neutrophil count
6
74.6
body mass index
6
71.4
body mass index
6
71.4
daytime rest measurement
2
70.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RAB GTPase activating protein 1 like
VGNC:11811
457532
Macaque
RAB GTPase activating protein 1 like
708179
Mouse
MGI:1352507
29809
Rat
RGD:1304620
304914
Horse
RAB GTPase activating protein 1 like [Source:HGNC Symbol;Acc:HGNC:24663]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RAB GTPase activating protein 1 like
Macaque
RAB GTPase activating protein 1 like
Mouse
Rat
Horse
RAB GTPase activating protein 1 like [Source:HGNC Symbol;Acc:HGNC:24663]
Publication Statistics
PubMed Score 5.57
PubMed score by year
PubTator Score 6.06
PubTator score by year
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Related Publications
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PMID
Year
Title