B3GNT6
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
Protein Summary
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs. The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]
- ENST00000622824
- ENSP00000484640
- ENSG00000198488
- BGnT-6
- B3Gn-T6
- beta3Gn-T6
- beta-1,3-Gn-T6
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
phenotype | 0.79 | ||
cell line | 0.56 | ||
cellular component | 0.55 | ||
gene perturbation | 0.48 | ||
protein complex | 0.4 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 10.57 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 88 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 10.57 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 88 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 11
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0