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Tdark
FAM25A
Protein FAM25A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343959
  • ENSP00000342790
  • ENSG00000188100

Symbol
  • bA96C23.5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 14   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 14   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
1
2
61.4
heel bone mineral density
1
1
1
56.6
hematocrit
1
1
1
51.4
1
1
0
1.5
45.2
leukocyte count
1
1
1
27.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
61.4
heel bone mineral density
1
56.6
hematocrit
1
51.4
0
1.5
45.2
leukocyte count
1
27.3
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
protein FAM25A
694015
Mouse
MGI:1916384
69134
Rat
RGD:1584388
684972
Species
Name
OMA
EggNOG
Inparanoid
Macaque
protein FAM25A
Mouse
Rat
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-B3EWG3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (10)
1 – 10 of 10
CASTOR2
Tbio
Novelty:  0.3255398
Score:  0.66
Data Source:  STRINGDB
MMRN2
Tbio
Novelty:  0.11135003
Score:  0.617
Data Source:  STRINGDB
RGPD5
Tbio
Novelty:  0.13776125
Score:  0.611
Data Source:  STRINGDB
ADIRF
Tbio
Novelty:  0.03346316
Score:  0.595
Data Source:  STRINGDB
AGAP5
Tdark
Family:  Enzyme
Novelty:  1.23602896
Score:  0.571
Data Source:  STRINGDB
RGPD8
Tdark
Novelty:  0.12397737
Score:  0.547
Data Source:  STRINGDB
CRCT1
Tbio
Novelty:  0.09048426
Score:  0.473
Data Source:  STRINGDB
RPP25
Tbio
Family:  Enzyme
Novelty:  0.07178063
Score:  0.472
Data Source:  STRINGDB
SNCG
Tbio
Novelty:  0.00446367
Score:  0.443
Data Source:  STRINGDB
THSD7A
Tbio
Novelty:  0.01515873
Score:  0.43
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.27

PubMed score by year
PubTator Score  0.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer