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Tdark
ZNF487
Putative zinc finger protein 487

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000437590
  • ENSP00000392335
  • ENSG00000243660

Symbol
  • KRBO1
  • ZNF487P
  • KRBO1
  • ZNF487P
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.81
histone modification site profile
0.77
tissue
0.66
cell line
0.58
cellular component
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.3   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 1   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.3   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 1   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
1
1
52.4
Hirschsprung disease
1
1
0
1.9
21
platelet crit
1
1
1
14.1
blood urea nitrogen measurement
1
1
1
10.5
heel bone mineral density
1
1
1
7.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
52.4
Hirschsprung disease
0
1.9
21
platelet crit
1
14.1
blood urea nitrogen measurement
1
10.5
heel bone mineral density
1
7.7
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-B1APH4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (10)
1 – 10 of 10
ZNF488
Tdark
Novelty:  0.41027707
Score:  0.552
Data Source:  STRINGDB
MPPE1
Tbio
Family:  Enzyme
Novelty:  0.16027847
Score:  0.541
Data Source:  STRINGDB
TOM1L2
Tdark
Novelty:  0.1647296
Score:  0.529
Data Source:  STRINGDB
ARL4A
Tbio
Family:  Enzyme
Novelty:  0.1083208
Score:  0.496
Data Source:  STRINGDB
WDR33
Tbio
Novelty:  0.09221439
Score:  0.495
Data Source:  STRINGDB
MAST2
Tbio
Family:  Kinase
Novelty:  0.02978977
Score:  0.447
Data Source:  STRINGDB
SIGLEC10
Tbio
Novelty:  0.02858542
Score:  0.445
Data Source:  STRINGDB
TSPAN33
Tbio
Novelty:  0.17463296
Score:  0.444
Data Source:  STRINGDB
RHOT1
Tbio
Family:  Enzyme
Novelty:  0.01411527
Score:  0.424
Data Source:  STRINGDB
PHLPP2
Tbio
Family:  Enzyme
Novelty:  0.02479769
Score:  0.41
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.30

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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