AZIN1
Antizyme inhibitor 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.97 | ||
protein domain | 0.92 | ||
transcription factor perturbation | 0.84 | ||
disease perturbation | 0.79 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Metabolism of polyamines | ||||
Reactome | Regulation of ornithine decarboxylase (ODC) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Metabolism of polyamines | ||||
Regulation of ornithine decarboxylase (ODC) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil count | 3 | 3 | 3 | 89.7 | |||||
leukocyte count | 2 | 2 | 2 | 84.5 | |||||
high density lipoprotein cholesterol measurement | 2 | 2 | 2 | 79.6 | |||||
reticulocyte measurement | 1 | 1 | 1 | 72.5 | |||||
alkaline phosphatase measurement | 2 | 2 | 1 | 6.3 | 62.6 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil count | 3 | 89.7 | |||||
leukocyte count | 2 | 84.5 | |||||
high density lipoprotein cholesterol measurement | 2 | 79.6 | |||||
reticulocyte measurement | 1 | 72.5 | |||||
alkaline phosphatase measurement | 1 | 6.3 | 62.6 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | antizyme inhibitor 1 | VGNC:916 | 464324 | |||||
Macaque | antizyme inhibitor 1 | 693581 | ||||||
Mouse | MGI:1859169 | 54375 | ||||||
Rat | RGD:61934 | 58961 | ||||||
Dog | antizyme inhibitor 1 | VGNC:38329 | 475058 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | antizyme inhibitor 1 | |||||
Macaque | antizyme inhibitor 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | antizyme inhibitor 1 | |||||
PMID | Year | Title |
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