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Tbio
AVL9
Late secretory pathway protein AVL9 homolog

Protein Summary
Description
Functions in cell migration.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318709
  • ENSP00000315568
  • ENSG00000105778

Symbol
  • KIAA0241
  • KIAA0241
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.74
virus perturbation
0.68
kinase perturbation
0.66
tissue sample
0.59
transcription factor binding site profile
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.89   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.89   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
FAM19A4
Tbio
Novelty:  0.04305684
p_int:  0.999994879
p_ni:  3.3e-7
p_wrong:  0.000004791
Score:  0.232
Data Source:  BioPlex,STRINGDB
LCHN
Tdark
Novelty:  0.08678963
Score:  0.925
Data Source:  STRINGDB
DENND6A
Tbio
Novelty:  4.5572617
Score:  0.905
Data Source:  STRINGDB
FAM45A
Tdark
Novelty:  0.94034891
Score:  0.905
Data Source:  STRINGDB
DNM1L
Tchem
Novelty:  0.00151314
Score:  0.816
Data Source:  STRINGDB
KBTBD2
Tdark
Novelty:  0.50755656
Score:  0.778
Data Source:  STRINGDB
RNF152
Tbio
Family:  Enzyme
Novelty:  0.16633202
Score:  0.724
Data Source:  STRINGDB
SNAPC4
Tbio
Family:  TF
Novelty:  0.09720791
Score:  0.713
Data Source:  STRINGDB
RNF31
Tbio
Family:  Enzyme
Novelty:  0.01394304
Score:  0.681
Data Source:  STRINGDB
RIC1
Tbio
Novelty:  0.04422709
Score:  0.633
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
3
3
3
59.5
intelligence
4
3
1
5.7
58.2
mathematical ability
2
2
2
44.1
cognitive function measurement
3
1
3
11.3
1
1
1
8.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
3
59.5
intelligence
1
5.7
58.2
mathematical ability
2
44.1
cognitive function measurement
3
11.3
1
8.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
AVL9 cell migration associated
VGNC:7348
472342
Macaque
AVL9 cell migration associated
693868
Mouse
MGI:1926187
78937
Rat
RGD:1564615
312371
Dog
AVL9 cell migration associated
VGNC:38316
482390
Species
Name
OMA
EggNOG
Inparanoid
Chimp
AVL9 cell migration associated
Macaque
AVL9 cell migration associated
Mouse
Rat
Dog
AVL9 cell migration associated
Publication Statistics
PubMed Score 10.89
PubMed score by year
PubTator Score 3.20
PubTator score by year
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Related Publications
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PMID
Year
Title