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Tdark
ATAD3C
ATPase family AAA domain-containing protein 3C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378785
  • ENSP00000368062
  • ENSG00000215915
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.9
molecular function
0.73
interacting protein
0.66
cellular component
0.6
protein domain
0.58


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.56   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
DKK3
Tbio
Novelty:  0.00519275
p_int:  0.999960794
p_ni:  0.000039205
Score:  0.189
Data Source:  BioPlex,STRINGDB
PLCD4
Tbio
Family:  Enzyme
Novelty:  0.07014141
p_int:  0.991095156
p_ni:  0.008904844
Data Source:  BioPlex
COMMD1
Tbio
Novelty:  0.01349432
p_int:  0.836734295
p_ni:  0.163265699
p_wrong:  6e-9
Score:  0.186
Data Source:  BioPlex,STRINGDB
CYB5RL
Tdark
Family:  Enzyme
Novelty:  0.21850409
Score:  0.635
Data Source:  STRINGDB
PHB
Tbio
Novelty:  0.00178383
Score:  0.619
Data Source:  STRINGDB
ZNF714
Tdark
Family:  TF
Novelty:  0.73743398
Score:  0.59
Data Source:  STRINGDB
C8orf44
Tdark
Novelty:  4.22913257
Score:  0.585
Data Source:  STRINGDB
OXA1L
Tbio
Novelty:  0.00235517
Score:  0.58
Data Source:  STRINGDB
GOLGA6L9
Tdark
Novelty:  34.44705882
Score:  0.534
Data Source:  STRINGDB
ANAPC16
Tdark
Family:  Enzyme
Novelty:  0.06353035
Score:  0.533
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intraocular pressure measurement
1
2
2
52.7
serum albumin measurement
1
1
1
33.1
heel bone mineral density
1
1
1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
intraocular pressure measurement
2
52.7
serum albumin measurement
1
33.1
heel bone mineral density
1
6.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ATPase family, AAA domain containing 3C
VGNC:8028
742484
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ATPase family, AAA domain containing 3C
Publication Statistics
PubMed Score 2.56
PubMed score by year
PubTator Score 1.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title