You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ASNSD1
Asparagine synthetase domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260952
  • ENSP00000260952
  • ENSG00000138381

Symbol
  • NS3TP1
  • NS3TP1
  • NBLA00058
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
protein domain
0.73
virus perturbation
0.72
transcription factor binding site profile
0.71
cell type or tissue
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.73   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 134   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.73   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 134   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (75)
PDZK1P1
Tdark
p_int:  0.999999972
p_ni:  2.8e-8
Data Source:  BioPlex
PTPRA
Tchem
Family:  Enzyme
Novelty:  0.01392344
p_int:  0.999999969
p_ni:  1.2e-8
p_wrong:  1.9e-8
Score:  0.21
Data Source:  BioPlex,STRINGDB
RFPL3
Tbio
Novelty:  0.44520296
p_int:  0.999999953
p_ni:  4.3e-8
p_wrong:  4e-9
Score:  0.416
Data Source:  BioPlex,STRINGDB
PPP1R35
Tdark
Family:  Enzyme
Novelty:  0.47022173
Score:  0.743
Data Source:  STRINGDB
HIBCH
Tbio
Family:  Enzyme
Novelty:  0.02964018
Score:  0.691
Data Source:  STRINGDB
ORMDL1
Tbio
Novelty:  0.1323746
Score:  0.676
Data Source:  STRINGDB
NEMP2
Tdark
Novelty:  1.47547409
Score:  0.668
Data Source:  STRINGDB
FAM193B
Tdark
Novelty:  1.69956634
Score:  0.659
Data Source:  STRINGDB
TMED9
Tbio
Novelty:  0.24024246
Score:  0.655
Data Source:  STRINGDB
CCT3
Tbio
Novelty:  0.01642521
Score:  0.649
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
2
2
4
74.1
hematocrit
2
2
4
61.8
red blood cell distribution width
2
1
4
48.5
erythrocyte count
1
1
2
28.1
fibroblast growth factor 23 measurement
1
1
2
17.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
4
74.1
hematocrit
4
61.8
red blood cell distribution width
4
48.5
erythrocyte count
2
28.1
fibroblast growth factor 23 measurement
2
17.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
asparagine synthetase domain containing 1
VGNC:97
459823
Macaque
asparagine synthetase domain containing 1
709388
Mouse
MGI:1917646
70396
Rat
RGD:1306332
299507
Dog
asparagine synthetase domain containing 1
VGNC:38183
478838
Species
Name
OMA
EggNOG
Inparanoid
Chimp
asparagine synthetase domain containing 1
Macaque
asparagine synthetase domain containing 1
Mouse
Rat
Dog
asparagine synthetase domain containing 1
Publication Statistics
PubMed Score 2.73
PubMed score by year
PubTator Score 0.05
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title