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Tchem
ASNS
Asparagine synthetase [glutamine-hydrolyzing]

Protein Summary
Description
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000175506
  • ENSP00000175506
  • ENSG00000070669
  • ENST00000394308
  • ENSP00000377845
  • ENST00000394309
  • ENSP00000377846
  • ENST00000422745
  • ENSP00000414901
  • ENST00000437628
  • ENSP00000414379
  • ENST00000444334
  • ENSP00000406994
  • ENST00000455086
  • ENSP00000408472

Symbol
  • TS11
  • TS11
  • ASNSD
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
kinase perturbation
0.99
PubMedID
0.99
gene perturbation
0.98
transcription factor perturbation
0.97


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 411.17   (req: < 5)
Gene RIFs: 36   (req: <= 3)
Antibodies: 328   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 411.17   (req: >= 5)
Gene RIFs: 36   (req: > 3)
Antibodies: 328   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 20
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 3
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0