ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.92 | ||
transcription factor perturbation | 0.91 | ||
transcription factor binding site profile | 0.82 | ||
kinase perturbation | 0.81 | ||
hub protein | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cargo trafficking to the periciliary membrane | ||||
Reactome | Cilium Assembly | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Reactome | VxPx cargo-targeting to cilium | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cargo trafficking to the periciliary membrane | ||||
Cilium Assembly | ||||
Organelle biogenesis and maintenance | ||||
VxPx cargo-targeting to cilium | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 2 | 3 | 94.8 | |||||
mean corpuscular volume | 1 | 1 | 1 | 85.3 | |||||
lymphocyte count | 2 | 2 | 2 | 84.7 | |||||
platelet count | 2 | 2 | 2 | 82.8 | |||||
red blood cell distribution width | 2 | 1 | 2 | 67.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 94.8 | |||||
mean corpuscular volume | 1 | 85.3 | |||||
lymphocyte count | 2 | 84.7 | |||||
platelet count | 2 | 82.8 | |||||
red blood cell distribution width | 2 | 67.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | VGNC:2459 | 464399 | |||||
Macaque | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 695681 | ||||||
Mouse | MGI:1342335 | 13196 | ||||||
Rat | RGD:1307379 | 314961 | ||||||
Dog | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | VGNC:38153 | 482044 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | |||||
Macaque | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | |||||
PMID | Year | Title |
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