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Tdark
ARMC6
Armadillo repeat-containing protein 6

Protein Summary
Description
The function of this gene's protein product has not been determined. A related protein in mouse suggests that this protein has a conserved function. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000269932
  • ENSP00000269932
  • ENSG00000105676
  • ENST00000392335
  • ENSP00000376147
  • ENST00000392336
  • ENSP00000376148
  • ENST00000535612
  • ENSP00000444156

Symbol
  • R30923_1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
small molecule perturbation
0.71
transcription factor binding site profile
0.68
tissue
0.64
cell type or tissue
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.19   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.19   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
SLC20A2
Tbio
Family:  Transporter
Novelty:  0.00387767
p_int:  0.999274285
p_ni:  0.000725706
p_wrong:  8e-9
Score:  0.175
Data Source:  BioPlex,STRINGDB
RMDN2
Tbio
Novelty:  0.10425524
p_int:  0.999234116
p_ni:  0.000566396
p_wrong:  0.000199489
Data Source:  BioPlex
MUL1
Tbio
Family:  Enzyme
Novelty:  0.00841786
p_int:  0.99896257
p_ni:  0.00103743
Data Source:  BioPlex
SLC27A2
Tbio
Family:  Transporter
Novelty:  0.01436035
p_int:  0.996703591
p_ni:  0.003296409
Data Source:  BioPlex
SLC16A10
Tbio
Family:  Transporter
Novelty:  0.02363735
p_int:  0.995228301
p_ni:  0.004771697
p_wrong:  2e-9
Score:  0.153
Data Source:  BioPlex,STRINGDB
C1orf159
Tdark
Novelty:  1.78509526
p_int:  0.992639208
p_ni:  0.007355822
p_wrong:  0.00000497
Score:  0.235
Data Source:  BioPlex,STRINGDB
B3GNT2
Tbio
Family:  Enzyme
Novelty:  0.02724566
p_int:  0.990519786
p_ni:  0.009480214
Data Source:  BioPlex
METTL9
Tdark
Family:  Enzyme
Novelty:  0.20589257
p_int:  0.963277526
p_ni:  0.036722475
Score:  0.183
Data Source:  BioPlex,STRINGDB
MICU2
Tbio
Novelty:  0.04146208
p_int:  0.928565127
p_ni:  0.071433882
p_wrong:  9.91e-7
Data Source:  BioPlex
DAAM1
Tbio
Novelty:  0.02143008
p_int:  0.857255804
p_ni:  0.142744196
Score:  0.157
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
2
2
88.3
low density lipoprotein cholesterol measurement
1
2
2
87.4
apolipoprotein B measurement
1
2
2
85.4
triglyceride measurement
1
2
2
83.7
bilirubin measurement
1
1
1
61.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
2
88.3
low density lipoprotein cholesterol measurement
2
87.4
apolipoprotein B measurement
2
85.4
triglyceride measurement
2
83.7
bilirubin measurement
1
61.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
armadillo repeat containing 6
VGNC:2105
455868
Macaque
armadillo repeat containing 6
720316
Mouse
MGI:1924063
76813
Dog
armadillo repeat containing 6
VGNC:38127
484811
Horse
armadillo repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:25049]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
armadillo repeat containing 6
Macaque
armadillo repeat containing 6
Mouse
Dog
armadillo repeat containing 6
Horse
armadillo repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:25049]
Publication Statistics
PubMed Score 1.19
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title