Pharos : Target Details

Tbio

Protein Summary

Uniprot Accession IDs

Gene Name

ARMC1

Ensembl ID

ENST00000276569
ENSP00000276569
ENSG00000104442
ENST00000458464
ENSP00000388572

Symbol

ARCP
Arcp

Illumination Graph

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.73

transcription factor binding site profile	0.72

histone modification site profile	0.68

transcription factor perturbation	0.68

kinase perturbation	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.02 (req: < 5)

View Publications

Gene RIFs: 2 (req: <= 3)

View Gene RIFs

Antibodies: 186 (req: <= 50)

View Antibodies

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 55.02 (req: >= 5)

Gene RIFs: 2 (req: > 3)

Antibodies: 186 (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

View GO Terms

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0

Expression Data (0 Tissues)

No expression data found

Protein Sequence and Structure

Residue Counts

Protein Sequence

Show Full Sequence

ProtVista Viewer

Related Tools (4)

Target Illumination GWAS Analytics (TIGA)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

View Data

Go To Tool

GENEVA

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

Go To Tool

GlyGen

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

Go To Tool

ARCHS4

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.

Go To Tool

Approved Drugs (0)

No approved drugs found

Active Ligands (0)

No active ligands found

Protein-Protein Interactions (61)

Explore Interacting Targets

1 – 10 of 61

See Interactions on String-DB

HSPBP1

Tbio

Novelty: 0.01176285

p_int: 0.99999433

p_ni: 0.00000567

Data Source: BioPlex

HSPA8

Tchem

Novelty: 0.00081014

p_int: 0.999989234

p_ni: 0.000010766

Data Source: BioPlex

HIST1H2BL

Tdark

Novelty: 0.64500134

p_int: 0.999983118

p_ni: 0.000016874

p_wrong: 8e-9

Score: 0.175

Data Source: BioPlex,STRINGDB

VSNL1

Tbio

Novelty: 0.01221371

p_int: 0.99997778

p_ni: 0.000022115

p_wrong: 1.05e-7

Score: 0.175

Data Source: BioPlex,STRINGDB

ATP4A

Tclin

Family: Transporter

Novelty: 0.00008783

p_int: 0.99987368

p_ni: 0.000099414

p_wrong: 0.000026905

Data Source: BioPlex

STX1B

Tbio

Novelty: 0.01171833

p_int: 0.999451381

p_ni: 0.000514673

p_wrong: 0.000033945

Score: 0.165

Data Source: BioPlex,STRINGDB

SYN1

Tbio

Novelty: 0.00093242

p_int: 0.999175447

p_ni: 0.000824553

Score: 0.165

Data Source: BioPlex,STRINGDB

DPYSL3

Tbio

Family: Enzyme

Novelty: 0.01284077

p_int: 0.998888325

p_ni: 0.001111675

Score: 0.351

Data Source: BioPlex,STRINGDB

CRMP1

Tbio

Family: Enzyme

Novelty: 0.01998451

p_int: 0.998580407

p_ni: 0.001419591

p_wrong: 2e-9

Score: 0.205

Data Source: BioPlex,STRINGDB

MAP2

Tbio

Novelty: 0.00068493

p_int: 0.997458158

p_ni: 0.002541764

p_wrong: 7.9e-8

Score: 0.165

Data Source: BioPlex,STRINGDB

Nearest Tclin Targets

Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.

Pathways (0)

No pathways found

Viral Interactions (0)

No viral interactions found

Gene Ontology Terms (2)

Functions (1)

Processes (1)

Find Similar Targets

Items per page:

1 – 1 of 1

GO Term	Evidence	Assigned by
metal ion binding	Inferred from Electronic Annotation (IEA)	InterPro

Disease Associations (null)

No disease associations found

GWAS Traits (4)

Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

1 – 4 of 4

GWAS Trait	EFO ID	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
self reported educational attainment	EFO_0004784	1	1	1		56.2

intelligence	EFO_0004337	2	2	1	5.5	39.4

cognitive function measurement	EFO_0008354	1	1	1		35

mathematical ability	EFO_0004875	1	1	1		35

Explore on Target Illumination GWAS Analytics (TIGA)

Items per page:

1 – 4 of 4

GWAS Trait	EFO ID	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
self reported educational attainment	EFO_0004784	1		56.2

intelligence	EFO_0004337	1	5.5	39.4

cognitive function measurement	EFO_0008354	1		35

mathematical ability	EFO_0004875	1		35

Beta Count

Odds Ratio

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UniProt Keyword

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GWAS Trait

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IDG Resources

No IDG generated resources found

Orthologs (13)

1 – 5 of 13

Species	Name	Source ID	Gene ID
Chimp	armadillo repeat containing 1	VGNC:917	464211

Macaque	armadillo repeat containing 1		702079

Mouse	armadillo repeat containing 1	MGI:1921502	74252

Rat	armadillo repeat containing 1	RGD:1560393	294948

Dog	armadillo repeat containing 1	VGNC:38123	486974

Species	Name	OMA	EggNOG	Inparanoid
Chimp	armadillo repeat containing 1

Macaque	armadillo repeat containing 1

Mouse	armadillo repeat containing 1

Rat	armadillo repeat containing 1

Dog	armadillo repeat containing 1

Publication Statistics

PubMed Score 55.02

PubMed score by year

PubTator Score 2.00

PubTator score by year

Related Publications

Text Mined References (9)

GeneRif Annotations (2)

Items per page:

0 of 0

PMID	Year	Title

No Header	No Header
Acetylation

Alternative splicing

Complete proteome

Phosphoprotein

Reference proteome