ARHGEF39
Rho guanine nucleotide exchange factor 39
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
microRNA | 0.75 | ||
gene perturbation | 0.68 | ||
transcription factor binding site profile | 0.63 | ||
tissue sample | 0.61 | ||
transcription factor perturbation | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell death signalling via NRAGE, NRIF and NADE | ||||
Reactome | Death Receptor Signalling | ||||
Reactome | G alpha (12/13) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | NRAGE signals death through JNK | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell death signalling via NRAGE, NRIF and NADE | ||||
Death Receptor Signalling | ||||
G alpha (12/13) signalling events | ||||
GPCR downstream signalling | ||||
NRAGE signals death through JNK | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
myeloid white cell count | 1 | 1 | 1 | 74.8 | |||||
lymphocyte count | 2 | 1 | 2 | 74.4 | |||||
leukocyte count | 1 | 1 | 1 | 68.6 | |||||
red blood cell distribution width | 1 | 1 | 1 | 64 | |||||
body height | 1 | 1 | 1 | 62.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
myeloid white cell count | 1 | 74.8 | |||||
lymphocyte count | 2 | 74.4 | |||||
leukocyte count | 1 | 68.6 | |||||
red blood cell distribution width | 1 | 64 | |||||
body height | 1 | 62.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Rho guanine nucleotide exchange factor 39 | VGNC:4617 | 465077 | |||||
Macaque | Rho guanine nucleotide exchange factor 39 | 696846 | ||||||
Mouse | MGI:3036286 | 230098 | ||||||
Rat | RGD:1310376 | 298404 | ||||||
Dog | Rho guanine nucleotide exchange factor 39 | VGNC:38088 | 611930 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Rho guanine nucleotide exchange factor 39 | |||||
Macaque | Rho guanine nucleotide exchange factor 39 | |||||
Mouse | ||||||
Rat | ||||||
Dog | Rho guanine nucleotide exchange factor 39 | |||||
PMID | Year | Title |
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