Tbio ARHGEF39 Rho guanine nucleotide exchange factor 39

Protein Summary

Description

Promotes cell proliferation.

Uniprot Accession IDs

• Q8N4T4
• Q49AG0
• Q6TPQ2
• Q96ST6

Gene Name

• ARHGEF39

Ensembl ID

• ENST00000378387
• ENSP00000367638
• ENSG00000137135
• ENST00000475323
• ENSP00000436519
• ENST00000490638
• ENSP00000436756

Symbol

• C9orf100
• C9orf100

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.75
gene perturbation	0.68
transcription factor binding site profile	0.63
tissue sample	0.61
transcription factor perturbation	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 76   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0