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Tbio
ARHGAP36
Rho GTPase-activating protein 36

Protein Summary
Description
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000276211
  • ENSP00000276211
  • ENSG00000147256
  • ENST00000370921
  • ENSP00000359959
  • ENST00000370922
  • ENSP00000359960
  • ENST00000412432
  • ENSP00000408515
  • ENST00000639280
  • ENSP00000492307
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
cell type or tissue
0.72
transcription factor
0.47
cell line
0.46
microRNA
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.92   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.92   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0