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Tbio
ARGLU1
Arginine and glutamate-rich protein 1

Protein Summary
Description
Required for the estrogen-dependent expression of ESR1 target genes. Can act in cooperation with MED1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000400198
  • ENSP00000383059
  • ENSG00000134884
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.96
virus perturbation
0.83
kinase perturbation
0.81
interacting protein
0.74
cell type or tissue
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
JMJD6
Tchem
Family:  Enzyme
Novelty:  0.00305479
p_int:  0.999980954
p_ni:  0.000018845
p_wrong:  2.01e-7
Data Source:  BioPlex
RPL14
Tbio
Novelty:  0.01600377
p_int:  0.995202413
p_ni:  0.000213267
p_wrong:  0.00458432
Score:  0.515
Data Source:  BioPlex,STRINGDB
NIFK
Tbio
Novelty:  0.01221562
p_int:  0.99114173
p_ni:  0.000238197
p_wrong:  0.008620073
Score:  0.281
Data Source:  BioPlex,STRINGDB
SRSF11
Tbio
Novelty:  0.17035604
Score:  0.916
Data Source:  STRINGDB
PUF60
Tbio
Novelty:  0.02667356
Score:  0.859
Data Source:  STRINGDB
SF3A2
Tbio
Novelty:  0.03658692
Score:  0.75
Data Source:  STRINGDB
SRPK2
Tchem
Family:  Kinase
Novelty:  0.03217228
Score:  0.725
Data Source:  STRINGDB
SNRNP70
Tbio
Novelty:  0.00116631
Score:  0.711
Data Source:  STRINGDB
PNISR
Tdark
Novelty:  0.06559175
Score:  0.711
Data Source:  STRINGDB
METTL14
Tbio
Family:  Enzyme
Novelty:  0.01377112
Score:  0.701
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
BHF-UCL
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
1
1
0
7.7
52.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
0
7.7
52.3
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
arginine and glutamate rich 1
VGNC:5043
452651
Mouse
MGI:2442985
234023
Rat
RGD:1310061
290912
Dog
arginine and glutamate rich 1
VGNC:38043
611747
Horse
arginine and glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:25482]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
arginine and glutamate rich 1
Mouse
Rat
Dog
arginine and glutamate rich 1
Horse
arginine and glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:25482]
Publication Statistics
PubMed Score 5.71
PubMed score by year
PubTator Score 3.94
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title