Protein Summary
Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.
- ENST00000254584
- ENSP00000254584
- ENSG00000132254
- ENST00000396777
- ENSP00000379998
- ENST00000423813
- ENSP00000398375
- ENST00000445086
- ENSP00000391427
- POR1
- POR1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.97 | ||
hub protein | 0.96 | ||
histone modification site profile | 0.92 | ||
microRNA | 0.72 | ||
kinase perturbation | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 83.65 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 226 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 83.65 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 226 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
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Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (60)
CALML3
Novelty: 0.0336689
p_int: 0.999760702
p_ni: 0.000239128
p_wrong: 1.7e-7
Data Source: BioPlex
LYPD3
Novelty: 0.03248533
p_int: 0.99947853
p_ni: 0.000517162
p_wrong: 0.000004307
Data Source: BioPlex
IFT20
Novelty: 0.03005088
p_int: 0.998841636
p_ni: 0.001156084
p_wrong: 0.00000228
Data Source: BioPlex
TMEM31
Novelty: 0.65381391
p_int: 0.991600033
p_ni: 0.001738034
p_wrong: 0.006661933
Data Source: BioPlex
DUSP22
Family: Enzyme
Novelty: 0.01579003
p_int: 0.967102726
p_ni: 0.00646234
p_wrong: 0.026434934
Score: 0.159
Data Source: BioPlex,STRINGDB
ARFIP1
Novelty: 0.20178246
p_int: 0.951297303
p_ni: 0.048702697
Score: 0.435
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (1063)
Reactome (4)
PathwayCommons (2)
WikiPathways (1057)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Reactome | Membrane Trafficking | ||||
Reactome | Retrograde transport at the Trans-Golgi-Network | ||||
Reactome | Vesicle-mediated transport | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Membrane Trafficking | ||||
Retrograde transport at the Trans-Golgi-Network | ||||
Vesicle-mediated transport | ||||
Viral Interactions (0)
Gene Ontology Terms (19)
Functions (8)
Components (6)
Processes (5)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | FlyBase | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (15)
1 – 5 of 15
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | ADP ribosylation factor interacting protein 2 | VGNC:3213 | 450994 | |||||
Macaque | ADP ribosylation factor interacting protein 2 | 710929 | ||||||
Mouse | MGI:1924182 | 76932 | ||||||
Rat | RGD:1303204 | 293344 | ||||||
Dog | ADP ribosylation factor interacting protein 2 | VGNC:38039 | 610132 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | ADP ribosylation factor interacting protein 2 | |||||
Macaque | ADP ribosylation factor interacting protein 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ADP ribosylation factor interacting protein 2 | |||||
Publication Statistics
PubMed Score 83.65
PubMed score by year
PubTator Score 121.03
PubTator score by year
Related Publications
Text Mined References (21)
GeneRif Annotations (6)
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PMID | Year | Title |
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