Tbio ARFIP2 Arfaptin-2

Protein Summary

Description

Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.

Uniprot Accession IDs

• P53365
• B4DX86
• B4E306
• D3DQT5

Gene Name

• ARFIP2

Ensembl ID

• ENST00000254584
• ENSP00000254584
• ENSG00000132254
• ENST00000396777
• ENSP00000379998
• ENST00000423813
• ENSP00000398375
• ENST00000445086
• ENSP00000391427

Symbol

• POR1
• POR1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.97
hub protein	0.96
histone modification site profile	0.92
microRNA	0.72
kinase perturbation	0.71

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / G-protein Modulator / Arfaptin-2

DTO Classes

Protein / Enzyme Modulator / G-protein Modulator / Arfaptin-2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 205.42   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 226   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 205.42   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 226   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0