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Tbio
ARFIP1
Arfaptin-1

Protein Summary
Description
Putative target protein of ADP-ribosylation factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000353617
  • ENSP00000296557
  • ENSG00000164144
  • ENST00000356064
  • ENSP00000348360
  • ENST00000405727
  • ENSP00000384189
  • ENST00000429148
  • ENSP00000396653
  • ENST00000451320
  • ENSP00000395083

Symbol
  • HSU52521
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
interacting protein
0.74
transcription factor binding site profile
0.74
tissue sample
0.68
microRNA
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.07   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 230   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.07   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 230   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (107)
CLPB
Tbio
Family:  Enzyme
Novelty:  0.00209789
p_int:  0.999459905
p_ni:  0.000540095
Score:  0.198
Data Source:  BioPlex,STRINGDB
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.999126678
p_ni:  0.000873322
Data Source:  BioPlex
PICK1
Tbio
Novelty:  0.0058265
p_int:  0.989210441
p_ni:  0.010789559
Score:  0.33
Data Source:  BioPlex,STRINGDB
ARFIP2
Tbio
Novelty:  0.01200959
p_int:  0.951297303
p_ni:  0.048702697
Score:  0.435
Data Source:  BioPlex,STRINGDB
HSPBP1
Tbio
Novelty:  0.01176285
p_int:  0.904756954
p_ni:  0.095243046
Score:  0.499
Data Source:  BioPlex,STRINGDB
HSD17B8
Tbio
Family:  Enzyme
Novelty:  0.00915958
Score:  0.862
Data Source:  STRINGDB
ARF3
Tbio
Family:  Enzyme
Novelty:  0.00336831
Score:  0.821
Data Source:  STRINGDB
ARF5
Tbio
Family:  Enzyme
Novelty:  0.02454098
Score:  0.815
Data Source:  STRINGDB
ARL1
Tbio
Family:  Enzyme
Novelty:  0.29930049
Score:  0.786
Data Source:  STRINGDB
TMEM131L
Tbio
Novelty:  0.60395527
Score:  0.783
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
2
4
82.7
reticulocyte count
2
2
2
66.6
mean platelet volume
1
1
1
63.4
reticulocyte measurement
2
1
2
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
82.7
reticulocyte count
2
66.6
mean platelet volume
1
63.4
reticulocyte measurement
2
54.4
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ADP ribosylation factor interacting protein 1
VGNC:2946
742995
Macaque
ADP ribosylation factor interacting protein 1
697533
Mouse
MGI:1277120
99889
Rat
RGD:708401
60382
Dog
ADP ribosylation factor interacting protein 1
VGNC:38038
475467
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ADP ribosylation factor interacting protein 1
Macaque
ADP ribosylation factor interacting protein 1
Mouse
Rat
Dog
ADP ribosylation factor interacting protein 1
Publication Statistics
PubMed Score 6.07
PubMed score by year
PubTator Score 6.82
PubTator score by year
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Related Publications
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PMID
Year
Title