You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
APOA2
Apolipoprotein A-II

Protein Summary
Description
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367990
  • ENSP00000356969
  • ENSG00000158874

Symbol
  • apoAII
  • Apo-AII
  • ApoA-II
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
1
molecular function
0.99
disease perturbation
0.87
biological term
0.72
disease
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 788.71   (req: < 5)
Gene RIFs: 76   (req: <= 3)
Antibodies: 476   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 788.71   (req: >= 5)
Gene RIFs: 76   (req: > 3)
Antibodies: 476   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 57
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0