Tbio AP5M1 AP-5 complex subunit mu-1

Protein Summary

Description

As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death.

Uniprot Accession IDs

• Q9H0R1
• O95354
• Q6ZMD7
• Q96DX3
• Q9NVC5

Gene Name

• AP5M1

Ensembl ID

• ENST00000261558
• ENSP00000261558
• ENSG00000053770

Symbol

• C14orf108
• MUDENG
• Mu5
• MuD
• MUDENG
• C14orf108

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.87
transcription factor binding site profile	0.76
kinase perturbation	0.71
cellular component	0.69
transcription factor perturbation	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 263.67   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 54   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 263.67   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0