AP2S1
AP-2 complex subunit sigma
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.95 | ||
interacting protein | 0.9 | ||
co-expressed gene | 0.82 | ||
disease perturbation | 0.74 | ||
transcription factor perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Axon guidance | ||||
Reactome | Beta-catenin independent WNT signaling | ||||
Reactome | Cargo recognition for clathrin-mediated endocytosis | ||||
Reactome | Clathrin-mediated endocytosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Axon guidance | ||||
Beta-catenin independent WNT signaling | ||||
Cargo recognition for clathrin-mediated endocytosis | ||||
Clathrin-mediated endocytosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
Non-traceable Author Statement (NAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
smoking status measurement | 1 | 1 | 1 | 31.4 | |||||
sun exposure measurement | 1 | 1 | 0 | 11.3 | 17.8 | ||||
eye measurement | 1 | 1 | 0 | 11.3 | 17.8 | ||||
low density lipoprotein cholesterol measurement | 1 | 1 | 1 | 2.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
smoking status measurement | 1 | 31.4 | |||||
sun exposure measurement | 0 | 11.3 | 17.8 | ||||
eye measurement | 0 | 11.3 | 17.8 | ||||
low density lipoprotein cholesterol measurement | 1 | 2.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | adaptor related protein complex 2 subunit sigma 1 | VGNC:6612 | 456156 | |||||
Macaque | adaptor related protein complex 2 sigma 1 subunit | 716911 | ||||||
Mouse | MGI:2141861 | 232910 | ||||||
Rat | RGD:620188 | 65046 | ||||||
Dog | adaptor related protein complex 2 subunit sigma 1 | VGNC:37962 | 476427 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | adaptor related protein complex 2 subunit sigma 1 | |||||
Macaque | adaptor related protein complex 2 sigma 1 subunit | |||||
Mouse | ||||||
Rat | ||||||
Dog | adaptor related protein complex 2 subunit sigma 1 | |||||
PMID | Year | Title |
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