AOC3
Membrane primary amine oxidase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.97 | ||
PubMedID | 0.86 | ||
protein domain | 0.85 | ||
biological term | 0.72 | ||
gene perturbation | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Metabolism | ||||
Reactome | Phase I - Functionalization of compounds | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Metabolism | ||||
Phase I - Functionalization of compounds | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 2 | 3 | 3 | 72.9 | |||||
waist-hip ratio | 1 | 2 | 2 | 62 | |||||
triglyceride measurement | 1 | 1 | 1 | 33.1 | |||||
2 | 1 | 1 | 1.1 | 26.1 | |||||
pulse pressure measurement | 1 | 1 | 1 | 21.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 3 | 72.9 | |||||
waist-hip ratio | 2 | 62 | |||||
triglyceride measurement | 1 | 33.1 | |||||
1 | 1.1 | 26.1 | |||||
pulse pressure measurement | 1 | 21.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | amine oxidase, copper containing 3 | VGNC:6339 | 454702 | |||||
Macaque | amine oxidase, copper containing 3 | 711820 | ||||||
Mouse | MGI:1306797 | 11754 | ||||||
Dog | amine oxidase, copper containing 3 | VGNC:37949 | 480511 | |||||
Horse | membrane primary amine oxidase | 100065767 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | amine oxidase, copper containing 3 | |||||
Macaque | amine oxidase, copper containing 3 | |||||
Mouse | ||||||
Dog | amine oxidase, copper containing 3 | |||||
Horse | membrane primary amine oxidase | |||||
PMID | Year | Title |
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