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Tbio
ANXA13
Annexin A13

Protein Summary
Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262219
  • ENSP00000262219
  • ENSG00000104537
  • ENST00000419625
  • ENSP00000390809

Symbol
  • ANX13
  • ISA
  • ANX13
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.76
gene perturbation
0.65
trait
0.61
phenotype
0.58
protein domain
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.8   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 206   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 56.8   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 206   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
TUBGCP3
Tbio
Novelty:  0.0221126
p_int:  0.999998634
p_ni:  0.000001366
Score:  0.234
Data Source:  BioPlex,STRINGDB
DEUP1
Tbio
Novelty:  0.13274391
p_int:  0.999980259
p_ni:  0.000004738
p_wrong:  0.000015003
Score:  0.188
Data Source:  BioPlex,STRINGDB
APBB1IP
Tbio
Novelty:  0.01684051
p_int:  0.99997282
p_ni:  0.000023996
p_wrong:  0.000003184
Score:  0.519
Data Source:  BioPlex,STRINGDB
ANXA2
Tbio
Novelty:  0.00103362
p_int:  0.997750335
p_ni:  0.000014049
p_wrong:  0.002235617
Score:  0.557
Data Source:  BioPlex,STRINGDB
SRPRA
Tchem
Novelty:  0.01248718
p_int:  0.965466116
p_ni:  0.002185688
p_wrong:  0.032348196
Score:  0.215
Data Source:  BioPlex,STRINGDB
MSI2
Tbio
Novelty:  0.01716735
p_int:  0.964288709
p_ni:  0.000983098
p_wrong:  0.034728194
Score:  0.222
Data Source:  BioPlex,STRINGDB
RHNO1
Tbio
Novelty:  0.03103
Score:  0.836
Data Source:  STRINGDB
CSMD3
Tbio
Novelty:  0.05973987
Score:  0.8
Data Source:  STRINGDB
DYSF
Tbio
Novelty:  0.00248634
Score:  0.753
Data Source:  STRINGDB
EXT1
Tbio
Family:  Enzyme
Novelty:  0.00355951
Score:  0.71
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
1
2
23
71.4
heel bone mineral density
2
3
3
68.8
intraocular pressure measurement
2
2
2
68.5
carotid artery intima media thickness
2
1
2
12
1
1
0
1.1
10.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
electrocardiography
23
71.4
heel bone mineral density
3
68.8
intraocular pressure measurement
2
68.5
carotid artery intima media thickness
2
12
0
1.1
10.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
annexin A13
VGNC:919
472914
Macaque
annexin A13
705013
Mouse
MGI:1917037
69787
Rat
RGD:1307545
362915
Dog
annexin A13
VGNC:37939
403935
Species
Name
OMA
EggNOG
Inparanoid
Chimp
annexin A13
Macaque
annexin A13
Mouse
Rat
Dog
annexin A13
Publication Statistics
PubMed Score 56.80
PubMed score by year
PubTator Score 53.87
PubTator score by year
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Related Publications
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PMID
Year
Title