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Tdark
ANKRD9
Ankyrin repeat domain-containing protein 9

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000286918
  • ENSP00000286918
  • ENSG00000156381
  • ENST00000559651
  • ENSP00000454100
  • ENST00000560748
  • ENSP00000453650
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.73
transcription factor
0.7
transcription factor binding site profile
0.69
cell type or tissue
0.65
transcription factor perturbation
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.66   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.66   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (185)
CES2
Tchem
Family:  Enzyme
Novelty:  0.00177726
p_int:  0.999992455
p_ni:  0.000007545
Data Source:  BioPlex
IMPDH1
Tclin
Family:  Enzyme
Novelty:  0.00758575
p_int:  0.999991106
p_ni:  0.000002868
p_wrong:  0.000006026
Score:  0.804
Data Source:  BioPlex,STRINGDB
KDM1B
Tbio
Family:  Epigenetic
Novelty:  0.02174039
p_int:  0.999912244
p_ni:  0.000087755
p_wrong:  1e-9
Data Source:  BioPlex
ZNHIT6
Tbio
Novelty:  1.1021845
p_int:  0.999839112
p_ni:  0.000160888
Data Source:  BioPlex
IMPDH2
Tclin
Family:  Enzyme
Novelty:  0.00815361
p_int:  0.998647425
p_ni:  0.001350326
p_wrong:  0.00000225
Score:  0.933
Data Source:  BioPlex,STRINGDB
ELOC
Tbio
Novelty:  0.00964847
p_int:  0.997528493
p_ni:  0.002471507
Score:  0.907
Data Source:  BioPlex,STRINGDB
SNX14
Tbio
Novelty:  0.10690692
p_int:  0.997241142
p_ni:  0.002758776
p_wrong:  8.2e-8
Data Source:  BioPlex
ELOB
Tbio
Novelty:  0.01315739
p_int:  0.968842909
p_ni:  0.031157091
Score:  0.901
Data Source:  BioPlex,STRINGDB
CRELD1
Tbio
Novelty:  0.04938248
p_int:  0.967477208
p_ni:  0.032522788
p_wrong:  4e-9
Data Source:  BioPlex
TIMM8B
Tbio
Family:  Enzyme
Novelty:  0.02843625
p_int:  0.960345171
p_ni:  0.039654829
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Neddylation
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Neddylation
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
4
5
4
2.6
88.6
platelet crit
2
2
2
68.8
eosinophil count
2
1
2
66.3
eosinophil percentage of leukocytes
1
1
1
58.4
hemoglobin measurement
2
2
2
47.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
4
2.6
88.6
platelet crit
2
68.8
eosinophil count
2
66.3
eosinophil percentage of leukocytes
1
58.4
hemoglobin measurement
2
47.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 9
VGNC:12974
467560
Macaque
ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096]
Mouse
MGI:1921501
74251
Rat
RGD:1307662
314457
Dog
ankyrin repeat domain 9
VGNC:37915
490865
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 9
Macaque
ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096]
Mouse
Rat
Dog
ankyrin repeat domain 9
Publication Statistics
PubMed Score 2.66
PubMed score by year
PubTator Score 0.28
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title