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Tbio
ANKRD55
Ankyrin repeat domain-containing protein 55

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.6   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.6   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
TTC30A
Tdark
Novelty:  1.41742212
p_int:  0.999996772
p_ni:  0.000003227
p_wrong:  1e-9
Score:  0.696
Data Source:  BioPlex,STRINGDB
IFT52
Tbio
Novelty:  0.04183122
p_int:  0.999996401
p_ni:  0.000003598
p_wrong:  1e-9
Score:  0.895
Data Source:  BioPlex,STRINGDB
IFT46
Tdark
Novelty:  0.11310911
p_int:  0.999937381
p_ni:  0.000062611
p_wrong:  8e-9
Score:  0.843
Data Source:  BioPlex,STRINGDB
IFT74
Tbio
Novelty:  0.07195266
p_int:  0.999808991
p_ni:  0.000191009
Score:  0.838
Data Source:  BioPlex,STRINGDB
TTC30B
Tbio
Novelty:  0.10944566
p_int:  0.998211781
p_ni:  0.001788212
p_wrong:  7e-9
Score:  0.691
Data Source:  BioPlex,STRINGDB
HIF1AN
Tbio
Novelty:  0.00861018
p_int:  0.959063627
p_ni:  0.040936373
Score:  0.253
Data Source:  BioPlex,STRINGDB
MIB1
Tbio
Family:  Enzyme
Novelty:  0.03288048
p_int:  0.854348401
p_ni:  0.145651599
Score:  0.188
Data Source:  BioPlex,STRINGDB
YWHAG
Tchem
Novelty:  0.00845572
p_int:  0.798076711
p_ni:  0.201923289
Score:  0.251
Data Source:  BioPlex,STRINGDB
YWHAZ
Tchem
Novelty:  0.00210582
p_int:  0.797989638
p_ni:  0.202010362
Score:  0.243
Data Source:  BioPlex,STRINGDB
TRIP6
Tbio
Novelty:  0.02183202
p_int:  0.780695899
p_ni:  0.219304101
Score:  0.283
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
8
3
3
1.2
97.1
multiple sclerosis
3
3
0
1.1
92.5
serum non-albumin protein measurement
1
3
3
87
2
2
0
1.1
83.5
blood protein measurement
2
2
2
80.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
1.2
97.1
multiple sclerosis
0
1.1
92.5
serum non-albumin protein measurement
3
87
0
1.1
83.5
blood protein measurement
2
80.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 55
VGNC:3901
461865
Mouse
MGI:1924568
77318
Rat
RGD:1307735
361898
Dog
ankyrin repeat domain 55
VGNC:37911
487214
Horse
ankyrin repeat domain 55
VGNC:15342
100061880
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 55
Mouse
Rat
Dog
ankyrin repeat domain 55
Horse
ankyrin repeat domain 55
Publication Statistics
PubMed Score 14.60
PubMed score by year
PubTator Score 7.88
PubTator score by year
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Related Publications
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PMID
Year
Title