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Tbio
ANKRD52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

Protein Summary
Description
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000267116
  • ENSP00000267116
  • ENSG00000139645

Symbol
  • ANKRD33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.77
microRNA
0.72
transcription factor binding site profile
0.69
gene perturbation
0.68
cell line
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.5   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.5   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (81)
PPP6R2
Tbio
Family:  Enzyme
Novelty:  0.12886225
p_int:  0.999999952
p_ni:  4.8e-8
Score:  0.731
Data Source:  BioPlex,STRINGDB
HIF1AN
Tbio
Novelty:  0.00861018
p_int:  0.999999191
p_ni:  8.09e-7
Score:  0.27
Data Source:  BioPlex,STRINGDB
DCLRE1C
Tbio
Novelty:  0.01064408
p_int:  0.999990694
p_ni:  0.000009306
Score:  0.307
Data Source:  BioPlex,STRINGDB
ZNF785
Tdark
Family:  TF
Novelty:  0.42629766
p_int:  0.999884242
p_ni:  0.000115758
Score:  0.201
Data Source:  BioPlex,STRINGDB
USP10
Tchem
Family:  Enzyme
Novelty:  0.05830541
p_int:  0.999817422
p_ni:  0.000182578
Score:  0.405
Data Source:  BioPlex,STRINGDB
TRMT2A
Tbio
Family:  Enzyme
Novelty:  0.15277091
p_int:  0.999145534
p_ni:  0.000854466
Score:  0.187
Data Source:  BioPlex,STRINGDB
ZNF263
Tbio
Family:  TF
Novelty:  0.098799
p_int:  0.996344672
p_ni:  0.003655328
Score:  0.217
Data Source:  BioPlex,STRINGDB
ZNF777
Tdark
Family:  TF
Novelty:  1.20195224
p_int:  0.994851655
p_ni:  0.005148345
Score:  0.175
Data Source:  BioPlex,STRINGDB
ELOA2
Tdark
Family:  Enzyme
Novelty:  0.7420148
p_int:  0.980331901
p_ni:  0.019663775
p_wrong:  0.000004325
Data Source:  BioPlex
ZNF414
Tdark
Novelty:  1.29024829
p_int:  0.969192759
p_ni:  0.030807241
Score:  0.196
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
5
10
11
99.6
5
4
0
1.4
84.7
1
2
0
1.5
66.6
psoriasis vulgaris
1
1
0
1.4
63.7
lymphocyte percentage of leukocytes
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
11
99.6
0
1.4
84.7
0
1.5
66.6
psoriasis vulgaris
0
1.4
63.7
lymphocyte percentage of leukocytes
1
35
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 52
VGNC:4924
451992
Mouse
MGI:2444029
237615
Rat
RGD:1307124
362811
Dog
ankyrin repeat domain 52
VGNC:37908
481109
Horse
ankyrin repeat domain 52
VGNC:15341
100059440
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 52
Mouse
Rat
Dog
ankyrin repeat domain 52
Horse
ankyrin repeat domain 52
Publication Statistics
PubMed Score 6.50
PubMed score by year
PubTator Score 1.17
PubTator score by year
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Related Publications
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PMID
Year
Title