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Tdark
ANKRD40
Ankyrin repeat domain-containing protein 40

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000285243
  • ENSP00000285243
  • ENSG00000154945
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
histone modification site profile
0.85
transcription factor binding site profile
0.85
small molecule perturbation
0.81
cell type or tissue
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.88   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 122   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.88   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 122   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (81)
C1orf94
Tdark
Novelty:  23
p_int:  0.999456143
p_ni:  0.000543856
p_wrong:  1e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
CES1
Tchem
Family:  Enzyme
Novelty:  0.00092608
p_int:  0.995129986
p_ni:  0.004869986
p_wrong:  2.7e-8
Score:  0.167
Data Source:  BioPlex,STRINGDB
AHCY
Tchem
Family:  Enzyme
Novelty:  0.00171812
p_int:  0.991064695
p_ni:  0.008935305
Score:  0.351
Data Source:  BioPlex,STRINGDB
PRDX2
Tbio
Novelty:  0.00189751
p_int:  0.989316198
p_ni:  0.010683801
Data Source:  BioPlex
RBFOX2
Tbio
Novelty:  0.00856339
p_int:  0.988517655
p_ni:  0.011482221
p_wrong:  1.24e-7
Data Source:  BioPlex
SOX5
Tbio
Family:  TF
Novelty:  0.00623121
p_int:  0.977851469
p_ni:  0.022148531
Score:  0.163
Data Source:  BioPlex,STRINGDB
RCBTB1
Tbio
Novelty:  0.12259073
p_int:  0.968848439
p_ni:  0.031151561
Score:  0.303
Data Source:  BioPlex,STRINGDB
LAGE3
Tdark
Novelty:  0.02099961
p_int:  0.968833422
p_ni:  0.031166578
Data Source:  BioPlex
SUMF2
Tbio
Family:  Enzyme
Novelty:  0.07551737
p_int:  0.966489865
p_ni:  0.033510135
Score:  0.228
Data Source:  BioPlex,STRINGDB
AGO2
Tbio
Novelty:  0.00057003
p_int:  0.963604529
p_ni:  0.036395466
p_wrong:  5e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
35
electrocardiography
1
1
4
26.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
35
electrocardiography
4
26.6
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
ankyrin repeat domain 40
706451
Mouse
MGI:1918702
71452
Rat
RGD:1594678
690586
Dog
ankyrin repeat domain 40
VGNC:37903
491085
Horse
ankyrin repeat domain 40
VGNC:15336
100070058
Species
Name
OMA
EggNOG
Inparanoid
Macaque
ankyrin repeat domain 40
Mouse
Rat
Dog
ankyrin repeat domain 40
Horse
ankyrin repeat domain 40
Publication Statistics
PubMed Score 0.88
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title