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Tdark
ANKRD39
Ankyrin repeat domain-containing protein 39

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393537
  • ENSP00000377170
  • ENSG00000213337
  • ENST00000443120
  • ENSP00000398321
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.7
cell type or tissue
0.65
transcription factor binding site profile
0.65
tissue sample
0.63
kinase perturbation
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.09   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.09   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (108)
CUL3
Tbio
Novelty:  0.0028737
p_int:  0.99999872
p_ni:  5e-9
p_wrong:  0.000001276
Score:  0.361
Data Source:  BioPlex,STRINGDB
FBXO17
Tbio
Novelty:  0.1320754
p_int:  0.999998555
p_ni:  2.61e-7
p_wrong:  0.000001184
Data Source:  BioPlex
CUL2
Tbio
Novelty:  0.00512916
p_int:  0.999930125
p_ni:  0.000051693
p_wrong:  0.000018182
Score:  0.203
Data Source:  BioPlex,STRINGDB
KCTD21
Tbio
Novelty:  1.05252269
p_int:  0.999929655
p_ni:  0.000068746
p_wrong:  0.000001599
Data Source:  BioPlex
UBA3
Tchem
Novelty:  0.03962261
p_int:  0.999785262
p_ni:  0.000214738
Data Source:  BioPlex
HERC4
Tbio
Family:  Enzyme
Novelty:  0.06392683
p_int:  0.999711822
p_ni:  0.000258926
p_wrong:  0.000029252
Data Source:  BioPlex
CRYZL1
Tbio
Family:  Enzyme
Novelty:  0.04435286
p_int:  0.999599451
p_ni:  0.000276654
p_wrong:  0.000123895
Data Source:  BioPlex
COPS7B
Tbio
Novelty:  0.63421506
p_int:  0.999555658
p_ni:  0.00044434
p_wrong:  2e-9
Data Source:  BioPlex
NAE1
Tchem
Novelty:  0.0283623
p_int:  0.999256881
p_ni:  0.000743119
Data Source:  BioPlex
ZC3HC1
Tbio
Novelty:  0.089692
p_int:  0.999094094
p_ni:  0.000905901
p_wrong:  5e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
calcium measurement
1
4
4
89.6
mathematical ability
3
1
3
53.7
serum non-albumin protein measurement
1
1
1
37.6
body height
1
1
1
32.7
birth weight
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
calcium measurement
4
89.6
mathematical ability
3
53.7
serum non-albumin protein measurement
1
37.6
body height
1
32.7
birth weight
1
31.4
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 39
VGNC:11
459422
Mouse
MGI:1914816
109346
Rat
RGD:1559504
367251
Dog
ankyrin repeat domain 39
VGNC:37902
474568
Horse
ankyrin repeat domain 39 [Source:HGNC Symbol;Acc:HGNC:28640]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat domain 39
Mouse
Rat
Dog
ankyrin repeat domain 39
Horse
ankyrin repeat domain 39 [Source:HGNC Symbol;Acc:HGNC:28640]
Publication Statistics
PubMed Score 0.09
PubMed score by year
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Related Publications
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PMID
Year
Title