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Tbio
ANGPTL7
Angiopoietin-related protein 7

Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.68   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 381   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.68   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 381   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
TFAP4
Tbio
Family:  TF
Novelty:  0.03155887
p_int:  0.999985333
p_ni:  0.000014667
Data Source:  BioPlex
HSD17B8
Tbio
Family:  Enzyme
Novelty:  0.00915958
p_int:  0.999930433
p_ni:  0.00006442
p_wrong:  0.000005148
Score:  0.163
Data Source:  BioPlex,STRINGDB
NMT1
Tchem
Family:  Enzyme
Novelty:  0.00343834
p_int:  0.975727712
p_ni:  0.024272288
Score:  0.183
Data Source:  BioPlex,STRINGDB
EDEM3
Tbio
Family:  Enzyme
Novelty:  0.09828323
p_int:  0.973389554
p_ni:  0.026610446
Score:  0.228
Data Source:  BioPlex,STRINGDB
EDEM2
Tbio
Family:  Enzyme
Novelty:  0.1180208
p_int:  0.965227963
p_ni:  0.034772037
Data Source:  BioPlex
KBTBD7
Tdark
Novelty:  0.4947466
p_int:  0.962044512
p_ni:  0.037955487
Data Source:  BioPlex
GNB2
Tbio
Novelty:  0.08682553
p_int:  0.931018694
p_ni:  0.068981285
p_wrong:  2.2e-8
Score:  0.215
Data Source:  BioPlex,STRINGDB
CCT6A
Tbio
Novelty:  0.02368046
p_int:  0.917212877
p_ni:  0.082787123
Score:  0.183
Data Source:  BioPlex,STRINGDB
CCT2
Tbio
Novelty:  0.01967139
p_int:  0.876344824
p_ni:  0.123655176
Data Source:  BioPlex
TCP1
Tbio
Novelty:  0.00395241
p_int:  0.843123671
p_ni:  0.156876329
Score:  0.23
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal topography
5
3
5
95.5
intraocular pressure measurement
1
2
2
85.8
sex hormone-binding globulin measurement
4
1
4
74.8
mean corpuscular volume
1
1
1
74.2
heel bone mineral density
2
1
2
72.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal topography
5
95.5
intraocular pressure measurement
2
85.8
sex hormone-binding globulin measurement
4
74.8
mean corpuscular volume
1
74.2
heel bone mineral density
2
72.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
angiopoietin like 7
VGNC:87
735739
Macaque
angiopoietin like 7
714204
Mouse
MGI:3605801
654812
Rat
RGD:7553363
102552055
Dog
angiopoietin like 7
VGNC:37863
608972
Species
Name
OMA
EggNOG
Inparanoid
Chimp
angiopoietin like 7
Macaque
angiopoietin like 7
Mouse
Rat
Dog
angiopoietin like 7
Publication Statistics
PubMed Score 32.68
PubMed score by year
PubTator Score 15.32
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title