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Tbio
ANGEL2
Protein angel homolog 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360506
  • ENSP00000353696
  • ENSG00000174606
  • ENST00000366962
  • ENSP00000355929
  • ENST00000535388
  • ENSP00000438141

Symbol
  • KIAA0759L
  • Ccr4d
  • KIAA0759L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.96
disease perturbation
0.87
kinase perturbation
0.84
transcription factor perturbation
0.8
transcription factor binding site profile
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
PRMT8
Tchem
Family:  Epigenetic
Novelty:  0.04213384
p_int:  0.999004537
p_ni:  0.000995463
Score:  0.286
Data Source:  BioPlex,STRINGDB
SYNCRIP
Tbio
Novelty:  0.01479381
p_int:  0.998401783
p_ni:  0.001597526
p_wrong:  6.91e-7
Score:  0.192
Data Source:  BioPlex,STRINGDB
FAM136A
Tdark
Novelty:  0.4050275
p_int:  0.99664433
p_ni:  0.003355663
p_wrong:  7e-9
Data Source:  BioPlex
ZFC3H1
Tbio
Novelty:  0.17313739
p_int:  0.995831455
p_ni:  0.004168534
p_wrong:  1.1e-8
Score:  0.255
Data Source:  BioPlex,STRINGDB
EEF1D
Tbio
Novelty:  0.02480745
p_int:  0.995765691
p_ni:  0.004234303
p_wrong:  6e-9
Score:  0.158
Data Source:  BioPlex,STRINGDB
NAA40
Tbio
Family:  Enzyme
Novelty:  0.13882523
p_int:  0.995602188
p_ni:  0.004397812
Score:  0.211
Data Source:  BioPlex,STRINGDB
RPS2
Tbio
Novelty:  0.00412313
p_int:  0.99496129
p_ni:  0.004894332
p_wrong:  0.000144378
Data Source:  BioPlex
HNRNPF
Tbio
Novelty:  0.01833966
p_int:  0.955297681
p_ni:  0.044702319
Score:  0.186
Data Source:  BioPlex,STRINGDB
HNRNPLL
Tbio
Novelty:  0.0498467
p_int:  0.931873853
p_ni:  0.068124618
p_wrong:  0.000001529
Data Source:  BioPlex
MRPL38
Tdark
Novelty:  0.71587283
p_int:  0.920207206
p_ni:  0.079473069
p_wrong:  0.000319725
Score:  0.164
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
62.1
mathematical ability
2
1
2
38.8
self reported educational attainment
1
1
1
37.6
reticulocyte measurement
1
1
1
29
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
62.1
mathematical ability
2
38.8
self reported educational attainment
1
37.6
reticulocyte measurement
1
29
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
angel homolog 2
VGNC:94
457726
Macaque
angel homolog 2
709819
Mouse
MGI:1196310
52477
Rat
RGD:1305056
305035
Dog
angel homolog 2
VGNC:37853
490287
Species
Name
OMA
EggNOG
Inparanoid
Chimp
angel homolog 2
Macaque
angel homolog 2
Mouse
Rat
Dog
angel homolog 2
Publication Statistics
PubMed Score 4.20
PubMed score by year
PubTator Score 2.00
PubTator score by year
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Related Publications
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PMID
Year
Title