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Tbio
ANGEL1
Protein angel homolog 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000251089
  • ENSP00000251089
  • ENSG00000013523

Symbol
  • KIAA0759
  • Ccr4e
  • KIAA0759
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.73
disease perturbation
0.62
histone modification site profile
0.57
cell line
0.55
tissue
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
EIF4E
Tchem
Novelty:  0.00072182
p_int:  0.99995712
p_ni:  0.000041937
p_wrong:  9.43e-7
Score:  0.677
Data Source:  BioPlex,STRINGDB
DISC1
Tbio
Novelty:  0.00183442
p_int:  0.999558282
p_ni:  0.000441709
p_wrong:  9e-9
Data Source:  BioPlex
ZNF414
Tdark
Novelty:  1.29024829
p_int:  0.994361626
p_ni:  0.00563511
p_wrong:  0.000003264
Score:  0.24
Data Source:  BioPlex,STRINGDB
APOBEC3D
Tbio
Novelty:  0.01102619
p_int:  0.988935294
p_ni:  0.011054534
p_wrong:  0.000010173
Data Source:  BioPlex
IQCN
Tdark
Novelty:  2.74045479
p_int:  0.969748459
p_ni:  0.030248562
p_wrong:  0.000002978
Data Source:  BioPlex
ZAR1L
Tdark
Novelty:  0.08793345
p_int:  0.964437299
p_ni:  0.021819183
p_wrong:  0.013743518
Data Source:  BioPlex
MTHFD1L
Tbio
Family:  Enzyme
Novelty:  0.01548353
p_int:  0.956227085
p_ni:  0.043760916
p_wrong:  0.000011999
Data Source:  BioPlex
FGFRL1
Tbio
Novelty:  0.02178846
p_int:  0.947009927
p_ni:  0.052949053
p_wrong:  0.00004102
Data Source:  BioPlex
SCNN1D
Tbio
Family:  IC
Novelty:  0.06191685
p_int:  0.937271409
p_ni:  0.062728591
Score:  0.175
Data Source:  BioPlex,STRINGDB
FBXO10
Tbio
Novelty:  0.18324932
p_int:  0.926608513
p_ni:  0.073309849
p_wrong:  0.000081639
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
2
2
1.1
47.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1.1
47.7
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
angel homolog 1
VGNC:3485
453059
Macaque
angel homolog 1
705043
Mouse
MGI:1915987
68737
Rat
RGD:1306238
362765
Dog
angel homolog 1
VGNC:37852
490800
Species
Name
OMA
EggNOG
Inparanoid
Chimp
angel homolog 1
Macaque
angel homolog 1
Mouse
Rat
Dog
angel homolog 1
Publication Statistics
PubMed Score 1.21
PubMed score by year
PubTator Score 1.67
PubTator score by year
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Related Publications
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PMID
Year
Title