Protein Summary
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
- ENST00000361355
- ENSP00000354610
- ENSG00000240038
- ENST00000477657
- ENSP00000433347
- ENST00000610648
- ENSP00000481588
- HXA
- AMY2
- AMY3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.97 | ||
cell line | 0.6 | ||
drug | 0.57 | ||
tissue sample | 0.51 | ||
metabolite | 0.45 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 88.01 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 190 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 88.01 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 190 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (52)
Nearest Tclin Targets (2)
Upstream (1)
Downstream (1)
1 – 1 of 1
Pathways (7)
Reactome (3)
KEGG (4)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Digestion | ||||
Reactome | Digestion and absorption | ||||
Reactome | Digestion of dietary carbohydrate | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Digestion | ||||
Digestion and absorption | ||||
Digestion of dietary carbohydrate | ||||
Viral Interactions (0)
Gene Ontology Terms (5)
Functions (3)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations (null)
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (1)
1 – 1 of 1
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Rat | RGD:2113 | 24203 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Rat | ||||||
Publication Statistics
PubMed Score 88.01
PubMed score by year
PubTator Score 22.90
PubTator score by year
Related Publications
Text Mined References (26)
GeneRif Annotations (2)
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