Protein Summary
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
- ENST00000361355
- ENSP00000354610
- ENSG00000240038
- ENST00000477657
- ENSP00000433347
- ENST00000610648
- ENSP00000481588
- HXA
- AMY2
- AMY3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.97 | ||
cell line | 0.6 | ||
drug | 0.57 | ||
tissue sample | 0.51 | ||
metabolite | 0.45 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 128.08 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 190 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 128.08 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 190 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0