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Tdark
AMMECR1L
AMMECR1-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000272647
  • ENSP00000272647
  • ENSG00000144233
  • ENST00000393001
  • ENSP00000376726
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.98
histone modification site profile
0.77
microRNA
0.77
virus perturbation
0.76
transcription factor perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.35   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 15   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.35   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 15   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
PGGT1B
Tchem
Family:  Enzyme
Novelty:  0.08041103
p_int:  0.999999989
p_ni:  6e-9
p_wrong:  4e-9
Score:  0.295
Data Source:  BioPlex,STRINGDB
FGL1
Tbio
Novelty:  0.02650803
p_int:  0.999987798
p_ni:  0.000012199
p_wrong:  3e-9
Data Source:  BioPlex
MAPK14
Tchem
Family:  Kinase
Novelty:  0.00045138
p_int:  0.99998508
p_ni:  0.000003902
p_wrong:  0.000011018
Score:  0.153
Data Source:  BioPlex,STRINGDB
MACF1
Tbio
Novelty:  0.0166336
p_int:  0.99990202
p_ni:  0.00009798
Score:  0.229
Data Source:  BioPlex,STRINGDB
FNTA
Tclin
Family:  Enzyme
Novelty:  0.03163169
p_int:  0.99976076
p_ni:  0.000019611
p_wrong:  0.00021963
Score:  0.311
Data Source:  BioPlex,STRINGDB
CC2D1B
Tbio
Novelty:  0.22031767
Score:  0.601
Data Source:  STRINGDB
GPATCH3
Tbio
Novelty:  0.71342982
Score:  0.599
Data Source:  STRINGDB
EDC3
Tbio
Novelty:  0.02077346
Score:  0.586
Data Source:  STRINGDB
C11orf54
Tbio
Family:  Enzyme
Novelty:  0.5374767
Score:  0.579
Data Source:  STRINGDB
ZKSCAN5
Tdark
Family:  TF
Novelty:  0.09717066
Score:  0.576
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
1
1
1
11.8
apolipoprotein A 1 measurement
1
1
1
10
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
1
11.8
apolipoprotein A 1 measurement
1
10
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
AMMECR1 like
VGNC:68
459598
Mouse
MGI:2442711
225339
Rat
RGD:1307915
307526
Dog
AMMECR1 like
VGNC:37834
483862
Horse
AMMECR1 like
VGNC:15280
100067484
Species
Name
OMA
EggNOG
Inparanoid
Chimp
AMMECR1 like
Mouse
Rat
Dog
AMMECR1 like
Horse
AMMECR1 like
Publication Statistics
PubMed Score 1.35
PubMed score by year
PubTator Score 0.60
PubTator score by year
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Related Publications
Items per page:
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PMID
Year
Title