Tbio ALPK3 Alpha-protein kinase 3

Protein Summary

Description

Involved in cardiomyocyte differentiation.

Uniprot Accession IDs

• Q96L96
• Q9P2L6

Gene Name

• ALPK3

Ensembl ID

• ENST00000258888
• ENSP00000258888
• ENSG00000136383

Symbol

• KIAA1330
• MAK
• MAK
• CMH27
• MIDORI

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
protein domain	0.85
kinase perturbation	0.81
interacting protein	0.72
tissue sample	0.62

Protein Classes

DTO Classes

Protein / Kinase / Protein Kinase / Atypical Group / Alpha Family / Alpha-protein Kinase 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.99   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 49   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.99   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0