ALOX15
Arachidonate 15-lipoxygenase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.96 | ||
protein domain | 0.92 | ||
biological term | 0.91 | ||
molecular function | 0.91 | ||
chemical | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Arachidonic acid metabolism | ||||
Reactome | Biosynthesis of DHA-derived SPMs | ||||
Reactome | Biosynthesis of DPA-derived SPMs | ||||
Reactome | Biosynthesis of DPAn-3 SPMs | ||||
Reactome | Biosynthesis of DPAn-3-derived protectins and resolvins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Arachidonic acid metabolism | ||||
Biosynthesis of DHA-derived SPMs | ||||
Biosynthesis of DPA-derived SPMs | ||||
Biosynthesis of DPAn-3 SPMs | ||||
Biosynthesis of DPAn-3-derived protectins and resolvins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
eosinophil count | 5 | 7 | 10 | 99.3 | |||||
eosinophil percentage of leukocytes | 2 | 7 | 8 | 99.1 | |||||
lymphocyte count | 3 | 3 | 3 | 93.2 | |||||
sum of eosinophil and basophil counts | 1 | 3 | 3 | 93 | |||||
eosinophil percentage of granulocytes | 1 | 2 | 2 | 86.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 10 | 99.3 | |||||
eosinophil percentage of leukocytes | 8 | 99.1 | |||||
lymphocyte count | 3 | 93.2 | |||||
sum of eosinophil and basophil counts | 3 | 93 | |||||
eosinophil percentage of granulocytes | 2 | 86.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | arachidonate 15-lipoxygenase | VGNC:9149 | 748294 | |||||
Macaque | arachidonate 15-lipoxygenase | 709212 | ||||||
Mouse | MGI:87997 | 11687 | ||||||
Rat | RGD:70493 | 81639 | ||||||
Dog | arachidonate 15-lipoxygenase | VGNC:37811 | 489458 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | arachidonate 15-lipoxygenase | |||||
Macaque | arachidonate 15-lipoxygenase | |||||
Mouse | ||||||
Rat | ||||||
Dog | arachidonate 15-lipoxygenase | |||||
PMID | Year | Title |
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