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Tbio
AKAP17A
A-kinase anchor protein 17A

Protein Summary
Description
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner. This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000313871
  • ENSP00000324827
  • ENSG00000197976
  • ENST00000474361
  • ENSP00000435479

Symbol
  • CXYorf3
  • DXYS155E
  • SFRS17A
  • XE7
  • XE7
  • 721P
  • XE7Y
  • CCDC133
  • CXYorf3
  • PRKA17A
  • SFRS17A
  • AKAP-17A
  • DXYS155E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.72
tissue sample
0.7
cellular component
0.67
kinase perturbation
0.6
tissue
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 95.8   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 206   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 95.8   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 206   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0