AIFM2
Apoptosis-inducing factor 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.81 | ||
cell type or tissue | 0.74 | ||
histone modification site profile | 0.73 | ||
cellular component | 0.68 | ||
tissue sample | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Reactome | TP53 Regulates Transcription of Cell Death Genes | ||||
Reactome | TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
TP53 Regulates Transcription of Cell Death Genes | ||||
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 1 | 1 | 1 | 38.8 | |||||
eyelid sagging measurement | 1 | 1 | 0 | 4 | 33.1 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 1 | 38.8 | |||||
eyelid sagging measurement | 0 | 4 | 33.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | apoptosis inducing factor, mitochondria associated 2 | 711037 | ||||||
Mouse | MGI:1918611 | 71361 | ||||||
Rat | RGD:1304964 | 361843 | ||||||
Dog | apoptosis inducing factor, mitochondria associated 2 | VGNC:37738 | 479236 | |||||
Horse | apoptosis inducing factor, mitochondria associated 2 | VGNC:15187 | 100063387 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | apoptosis inducing factor, mitochondria associated 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | apoptosis inducing factor, mitochondria associated 2 | |||||
Horse | apoptosis inducing factor, mitochondria associated 2 | |||||
PMID | Year | Title |
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