You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
AGMAT
Agmatinase, mitochondrial

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375826
  • ENSP00000364986
  • ENSG00000116771
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.62
histone modification site profile
0.59
protein domain
0.58
cell type or tissue
0.51
microRNA
0.48


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.45   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.45   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (86)
FNTA
Tclin
Family:  Enzyme
Novelty:  0.03163169
p_int:  0.999999375
p_ni:  1.26e-7
p_wrong:  4.99e-7
Data Source:  BioPlex
BTBD1
Tbio
Novelty:  0.19772296
p_int:  0.908367107
p_ni:  0.076664618
p_wrong:  0.014968275
Score:  0.169
Data Source:  BioPlex,STRINGDB
DPF3
Tbio
Family:  Epigenetic
Novelty:  0.069151
p_int:  0.831199711
p_ni:  0.003806056
p_wrong:  0.164994233
Score:  0.188
Data Source:  BioPlex,STRINGDB
ACAD9
Tbio
Family:  Enzyme
Novelty:  0.03238308
p_int:  0.764617096
p_ni:  0.235382904
Score:  0.199
Data Source:  BioPlex,STRINGDB
AZIN2
Tbio
Family:  Enzyme
Novelty:  0.00750311
Score:  0.993
Data Source:  STRINGDB
ODC1
Tclin
Family:  Enzyme
Novelty:  0.00037968
Score:  0.983
Data Source:  STRINGDB
SRM
Tchem
Family:  Enzyme
Novelty:  0.01583759
Score:  0.978
Data Source:  STRINGDB
AOC1
Tchem
Family:  Enzyme
Novelty:  0.00146464
Score:  0.953
Data Source:  STRINGDB
SAT1
Tbio
Family:  Enzyme
Novelty:  0.0022456
Score:  0.941
Data Source:  STRINGDB
SAT2
Tbio
Family:  Enzyme
Novelty:  0.10019856
Score:  0.907
Data Source:  STRINGDB
Pathways (7)
Agmatine biosynthesis (R-HSA-351143)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Agmatine biosynthesis
Reactome
Metabolism
Reactome
Metabolism of amino acids and derivatives
Reactome
Metabolism of polyamines
Name
Explore in Pharos
Explore in Source
Agmatine biosynthesis
Metabolism
Metabolism of amino acids and derivatives
Metabolism of polyamines
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
7
7
6
8.2
94.6
urate measurement
3
4
4
92.5
creatinine measurement
4
4
4
84.3
chronotype measurement
3
2
2
1
78.2
body mass index
2
2
2
49.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
6
8.2
94.6
urate measurement
4
92.5
creatinine measurement
4
84.3
chronotype measurement
2
1
78.2
body mass index
2
49.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
agmatinase
VGNC:10538
469130
Macaque
agmatinase
713190
Mouse
MGI:1923236
75986
Rat
RGD:1308424
298607
Dog
agmatinase
VGNC:37705
487430
Species
Name
OMA
EggNOG
Inparanoid
Chimp
agmatinase
Macaque
agmatinase
Mouse
Rat
Dog
agmatinase
Publication Statistics
PubMed Score 22.45
PubMed score by year
PubTator Score 21.01
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title