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Tdark
AGAP6
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6

Protein Summary
Description
Putative GTPase-activating protein.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374056
  • ENSP00000363168
  • ENSG00000204149
  • ENST00000412531
  • ENSP00000400972

Symbol
  • CTGLF3
  • AGAP-6
  • CTGLF3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
tissue
0.72
cell line
0.56
tissue sample
0.53
cellular component
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.02   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.02   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (9)
ANKRD31
Tdark
Novelty:  0.5338446
Score:  0.669
Data Source:  STRINGDB
GRAMD1A
Tbio
Novelty:  0.15461113
Score:  0.649
Data Source:  STRINGDB
ZNF620
Tdark
Family:  TF
Novelty:  2.57179565
Score:  0.648
Data Source:  STRINGDB
AHDC1
Tdark
Novelty:  0.06647774
Score:  0.59
Data Source:  STRINGDB
NOC3L
Tbio
Novelty:  0.05635731
Score:  0.528
Data Source:  STRINGDB
GPATCH2
Tdark
Novelty:  0.03284393
Score:  0.49
Data Source:  STRINGDB
RIPK4
Tchem
Family:  Kinase
Novelty:  0.00818379
Score:  0.488
Data Source:  STRINGDB
BTBD9
Tbio
Novelty:  0.02793632
Score:  0.488
Data Source:  STRINGDB
GABRD
Tclin
Family:  IC
Novelty:  0.0204242
Score:  0.402
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
42.3
mean reticulocyte volume
1
1
1
36.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
42.3
mean reticulocyte volume
1
36.5
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.02
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title