AFF4
AF4/FMR2 family member 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 0.99 | ||
transcription factor binding site profile | 0.87 | ||
transcription factor perturbation | 0.84 | ||
cell type or tissue | 0.77 | ||
microRNA | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Formation of RNA Pol II elongation complex | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | RNA Polymerase II Pre-transcription Events | ||||
Reactome | RNA Polymerase II Transcription | ||||
Reactome | RNA Polymerase II Transcription Elongation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Formation of RNA Pol II elongation complex | ||||
Gene expression (Transcription) | ||||
RNA Polymerase II Pre-transcription Events | ||||
RNA Polymerase II Transcription | ||||
RNA Polymerase II Transcription Elongation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
IGF-1 measurement | 1 | 2 | 2 | 80 | |||||
monocyte count | 1 | 1 | 1 | 78.6 | |||||
glomerular filtration rate | 3 | 2 | 3 | 76.7 | |||||
waist-hip ratio | 3 | 4 | 4 | 75.4 | |||||
waist circumference | 1 | 3 | 3 | 73.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
IGF-1 measurement | 2 | 80 | |||||
monocyte count | 1 | 78.6 | |||||
glomerular filtration rate | 3 | 76.7 | |||||
waist-hip ratio | 4 | 75.4 | |||||
waist circumference | 3 | 73.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | AF4/FMR2 family member 4 | VGNC:3897 | 107974861 | |||||
Macaque | AF4/FMR2 family member 4 | 709137 | ||||||
Mouse | MGI:2136171 | 93736 | ||||||
Rat | RGD:1311694 | 303132 | ||||||
Dog | AF4/FMR2 family member 4 | VGNC:37688 | 474678 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | AF4/FMR2 family member 4 | |||||
Macaque | AF4/FMR2 family member 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | AF4/FMR2 family member 4 | |||||
PMID | Year | Title |
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