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Tbio
ADPRHL1
[Protein ADP-ribosylarginine] hydrolase-like protein 1

Protein Summary
Description
ADP-ribosylation is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases (see ART1; MIM 601625) transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases, such as ADPRHL1, reverse the reaction (Glowacki et al., 2002 [PubMed 12070318]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356501
  • ENSP00000348894
  • ENSG00000153531
  • ENST00000375418
  • ENSP00000364567

Symbol
  • ARH2
  • ARH2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.66
gene perturbation
0.53
cell line
0.52
tissue sample
0.52
cell type or tissue
0.47


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.66   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.66   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0