You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ADAMTSL1
ADAMTS-like protein 1

Protein Summary
Description
This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000276935
  • ENSP00000276935
  • ENSG00000178031
  • ENST00000327883
  • ENSP00000327887
  • ENST00000380545
  • ENSP00000369918
  • ENST00000380548
  • ENSP00000369921
  • ENST00000380566
  • ENSP00000369940
  • ENST00000542621
  • ENSP00000440472

Symbol
  • ADAMTSR1
  • C9orf94
  • C9orf94
  • PUNCTIN
  • ADAMTSR1
  • ADAMTSL-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
protein domain
0.92
transcription factor perturbation
0.88
cell line
0.71
transcription factor
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.9   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 147   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.9   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 147   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0