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Tbio
ACTR6
Actin-related protein 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000188312
  • ENSP00000188312
  • ENSG00000075089

Symbol
  • ARP6
  • CDA12
  • hARP6
  • hARPX
  • HSPC281
  • MSTP136
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
transcription factor binding site profile
0.8
cell type or tissue
0.76
hub protein
0.71
virus perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.52   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.52   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (69)
HIST1H2BA
Tbio
Novelty:  0.02431803
p_int:  0.999999338
p_ni:  6.62e-7
Score:  0.542
Data Source:  BioPlex,STRINGDB
H2AFZ
Tbio
Novelty:  0.00222512
p_int:  0.999998256
p_ni:  0.000001744
Score:  0.858
Data Source:  BioPlex,STRINGDB
RUVBL1
Tbio
Novelty:  0.0089115
p_int:  0.999996785
p_ni:  0.000003215
Score:  0.788
Data Source:  BioPlex,STRINGDB
YEATS4
Tbio
Novelty:  0.02632024
p_int:  0.999996365
p_ni:  0.000003635
Score:  0.943
Data Source:  BioPlex,STRINGDB
RUVBL2
Tbio
Novelty:  0.01129017
p_int:  0.999977264
p_ni:  0.000022736
Score:  0.715
Data Source:  BioPlex,STRINGDB
ZNHIT1
Tbio
Novelty:  0.00390514
p_int:  0.999919739
p_ni:  0.000014006
p_wrong:  0.000066256
Score:  0.955
Data Source:  BioPlex,STRINGDB
NFATC2IP
Tbio
Novelty:  0.02974299
p_int:  0.999113585
p_ni:  0.000886415
Score:  0.817
Data Source:  BioPlex,STRINGDB
P4HA3
Tbio
Family:  Enzyme
Novelty:  0.03832564
p_int:  0.999107034
p_ni:  0.000892966
Score:  0.671
Data Source:  BioPlex,STRINGDB
SRCAP
Tbio
Family:  Enzyme
Novelty:  0.02446238
p_int:  0.997631288
p_ni:  0.002368712
Score:  0.956
Data Source:  BioPlex,STRINGDB
QPRT
Tbio
Family:  Enzyme
Novelty:  0.00781554
p_int:  0.973722412
p_ni:  0.026264451
p_wrong:  0.000013137
Score:  0.518
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
AgBase
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
gut microbiome measurement
2
1
0
5.8
7.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
gut microbiome measurement
0
5.8
7.9
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ARP6 actin related protein 6 homolog
VGNC:10077
452159
Macaque
ARP6 actin related protein 6 homolog
695055
Mouse
MGI:1914269
67019
Rat
RGD:1304609
314718
Dog
ARP6 actin related protein 6 homolog
VGNC:37556
475439
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ARP6 actin related protein 6 homolog
Macaque
ARP6 actin related protein 6 homolog
Mouse
Rat
Dog
ARP6 actin related protein 6 homolog
Publication Statistics
PubMed Score 9.52
PubMed score by year
PubTator Score 2.06
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title