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Tdark
ACBD7
Acyl-CoA-binding domain-containing protein 7

Protein Summary
Description
Binds medium- and long-chain acyl-CoA esters.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356189
  • ENSP00000367453
  • ENSG00000176244

Symbol
  • bA455B2.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.91
cellular component
0.75
tissue sample
0.74
microRNA
0.51
metabolite
0.46


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.85   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 122   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.85   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 122   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
OGDHL
Tbio
Family:  Enzyme
Novelty:  0.05079572
p_int:  0.999946044
p_ni:  0.000053718
p_wrong:  2.38e-7
Score:  0.193
Data Source:  BioPlex,STRINGDB
SRC
Tclin
Family:  Kinase
Novelty:  0.00008479
p_int:  0.999781684
p_ni:  0.000218315
p_wrong:  1e-9
Score:  0.168
Data Source:  BioPlex,STRINGDB
ACOX1
Tchem
Family:  Enzyme
Novelty:  0.00473427
p_int:  0.998928387
p_ni:  0.001071613
Score:  0.292
Data Source:  BioPlex,STRINGDB
HPCAL1
Tbio
Novelty:  0.04434155
p_int:  0.998832997
p_ni:  0.001165664
p_wrong:  0.000001339
Score:  0.169
Data Source:  BioPlex,STRINGDB
PAG1
Tbio
Novelty:  0.01390911
p_int:  0.990148026
p_ni:  0.009851971
p_wrong:  3e-9
Data Source:  BioPlex
GNAZ
Tbio
Novelty:  0.02008523
p_int:  0.973067535
p_ni:  0.022335923
p_wrong:  0.004596543
Data Source:  BioPlex
TBC1D24
Tbio
Novelty:  0.0161631
p_int:  0.957005183
p_ni:  0.007619771
p_wrong:  0.035375046
Score:  0.201
Data Source:  BioPlex,STRINGDB
SUGP1
Tbio
Novelty:  0.00434166
p_int:  0.946151177
p_ni:  0.053783139
p_wrong:  0.000065685
Score:  0.157
Data Source:  BioPlex,STRINGDB
PTPRG
Tchem
Family:  Enzyme
Novelty:  0.01920574
p_int:  0.929433748
p_ni:  0.070566207
p_wrong:  4.5e-8
Score:  0.16
Data Source:  BioPlex,STRINGDB
YES1
Tclin
Family:  Kinase
Novelty:  0.00534936
p_int:  0.880341966
p_ni:  0.119658034
Score:  0.272
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Fatty acid metabolism (R-HSA-8978868)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Fatty acid metabolism
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Mitochondrial Fatty Acid Beta-Oxidation
Name
Explore in Pharos
Explore in Source
Fatty acid metabolism
Metabolism
Metabolism of lipids
Mitochondrial Fatty Acid Beta-Oxidation
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
1
1
0.4
1
1
0
1.2
0.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
0.4
0
1.2
0.3
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
acyl-CoA binding domain containing 7
VGNC:11618
739212
Mouse
MGI:1925495
78245
Rat
RGD:1564164
361277
Horse
acyl-CoA binding domain containing 7
VGNC:14974
100630417
Cow
acyl-CoA binding domain containing 7
VGNC:25533
508284
Species
Name
OMA
EggNOG
Inparanoid
Chimp
acyl-CoA binding domain containing 7
Mouse
Rat
Horse
acyl-CoA binding domain containing 7
Cow
acyl-CoA binding domain containing 7
Publication Statistics
PubMed Score 2.85
PubMed score by year
PubTator Score 0.75
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title