ACAD11
Acyl-CoA dehydrogenase family member 11
Protein Summary
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015]
- ENST00000264990
- ENSP00000264990
- ENSG00000240303
- ACAD-11
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.89 | ||
transcription factor perturbation | 0.88 | ||
protein domain | 0.85 | ||
cell type or tissue | 0.82 | ||
molecular function | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.81 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 86 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.81 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 86 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (87)
IFT22
Family: Enzyme
Novelty: 0.18342877
p_int: 0.999991318
p_ni: 0.000008683
Data Source: BioPlex
CD2BP2
Novelty: 0.01440995
p_int: 0.999990047
p_ni: 0.000009953
Score: 0.539
Data Source: BioPlex,STRINGDB
BMT2
Family: Enzyme
Novelty: 0.05916379
p_int: 0.999956998
p_ni: 0.000043002
Data Source: BioPlex
PDYN
Novelty: 0.00039564
p_int: 0.999707951
p_ni: 0.000292049
Score: 0.167
Data Source: BioPlex,STRINGDB
PPP6R2
Family: Enzyme
Novelty: 0.12886225
p_int: 0.999245794
p_ni: 0.000754206
Data Source: BioPlex
Nearest Tclin Targets
Pathways (9)
Reactome (4)
PathwayCommons (5)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Fatty acid metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Mitochondrial Fatty Acid Beta-Oxidation | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Fatty acid metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Mitochondrial Fatty Acid Beta-Oxidation | ||||
Viral Interactions (0)
Gene Ontology Terms (11)
Functions (5)
Components (4)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (18)
Items per page:
1 – 5 of 18
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 3 | 4 | 94.5 | |||||
low density lipoprotein cholesterol measurement | 5 | 5 | 6 | 90.1 | |||||
alkaline phosphatase measurement | 2 | 2 | 1 | 6.7 | 86.8 | ||||
apolipoprotein B measurement | 2 | 3 | 3 | 86.7 | |||||
hemoglobin measurement | 2 | 2 | 2 | 79.5 | |||||
Items per page:
1 – 5 of 18
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
red blood cell distribution width | 4 | 94.5 | |||||
low density lipoprotein cholesterol measurement | 6 | 90.1 | |||||
alkaline phosphatase measurement | 1 | 6.7 | 86.8 | ||||
apolipoprotein B measurement | 3 | 86.7 | |||||
hemoglobin measurement | 2 | 79.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | acyl-CoA dehydrogenase family member 11 | VGNC:11320 | 100615854 | |||||
Mouse | MGI:2143169 | 102632 | ||||||
Rat | RGD:1306270 | 315973 | ||||||
Dog | acyl-CoA dehydrogenase family member 11 | VGNC:37491 | 100856488 | |||||
Horse | acyl-CoA dehydrogenase family member 11 | VGNC:14964 | 100629864 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | acyl-CoA dehydrogenase family member 11 | |||||
Mouse | ||||||
Rat | ||||||
Dog | acyl-CoA dehydrogenase family member 11 | |||||
Horse | acyl-CoA dehydrogenase family member 11 | |||||
Publication Statistics
PubMed Score 2.81
PubMed score by year
PubTator Score 1.97
PubTator score by year
Related Publications
Text Mined References (18)
GeneRif Annotations (4)
Items per page:
0 of 0
PMID | Year | Title |
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