ACAD10
Acyl-CoA dehydrogenase family member 10
Protein Summary
Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA. This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]
- ENST00000313698
- ENSP00000325137
- ENSG00000111271
- ENST00000455480
- ENSP00000389813
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 1 | ||
histone modification site profile | 0.94 | ||
molecular function | 0.67 | ||
transcription factor | 0.67 | ||
transcription factor binding site profile | 0.67 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.22 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 152 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.22 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 152 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 3
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0