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Tbio
ABLIM1
Actin-binding LIM protein 1

Protein Summary
Description
May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance. This gene encodes a LIM zinc-binding domain-containing protein that binds to actin filaments and mediates interactions between actin and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000277895
  • ENSP00000277895
  • ENSG00000099204
  • ENST00000369253
  • ENSP00000358257
  • ENST00000369256
  • ENSP00000358260
  • ENST00000392952
  • ENSP00000376679
  • ENST00000392955
  • ENSP00000376682

Symbol
  • ABLIM
  • KIAA0059
  • LIMAB1
  • ABLIM
  • LIMAB1
  • LIMATIN
  • abLIM-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
1
disease perturbation
0.99
hub protein
0.97
kinase
0.96
PubMedID
0.93


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.75   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 167   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.75   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 167   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0