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Tbio
ABI3BP
Target of Nesh-SH3

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.88   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 207   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.88   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 207   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
ABI3
Tbio
Novelty:  0.00891209
Score:  0.975
Data Source:  STRINGDB
ABI1
Tbio
Novelty:  0.00796638
Score:  0.645
Data Source:  STRINGDB
TMEM255B
Tdark
Novelty:  1.57149427
Score:  0.536
Data Source:  STRINGDB
KRBOX1
Tdark
Novelty:  3.9375
Score:  0.533
Data Source:  STRINGDB
LTBP3
Tbio
Novelty:  0.0190763
Score:  0.503
Data Source:  STRINGDB
ATP10B
Tdark
Family:  Transporter
Novelty:  0.11537156
Score:  0.498
Data Source:  STRINGDB
LRRIQ3
Tdark
Novelty:  0.63243484
Score:  0.487
Data Source:  STRINGDB
CCDC80
Tbio
Novelty:  0.01634056
Score:  0.483
Data Source:  STRINGDB
DCAF4L2
Tdark
Novelty:  0.55635961
Score:  0.473
Data Source:  STRINGDB
LTBP2
Tbio
Novelty:  0.013159
Score:  0.462
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc area measurement
2
2
3
83.4
optic disc size measurement
1
1
1
83.2
cup-to-disc ratio measurement
2
2
2
75
educational attainment
1
1
1
57.1
sex hormone-binding globulin measurement
2
1
2
28.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc area measurement
3
83.4
optic disc size measurement
1
83.2
cup-to-disc ratio measurement
2
75
educational attainment
1
57.1
sex hormone-binding globulin measurement
2
28.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ABI family member 3 binding protein
VGNC:11319
740047
Mouse
MGI:2444583
320712
Rat
RGD:1562717
363767
Dog
ABI family member 3 binding protein
VGNC:37477
478544
Opossum
ABI family member 3 binding protein [Source:HGNC Symbol;Acc:HGNC:17265]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ABI family member 3 binding protein
Mouse
Rat
Dog
ABI family member 3 binding protein
Opossum
ABI family member 3 binding protein [Source:HGNC Symbol;Acc:HGNC:17265]
Publication Statistics
PubMed Score 19.88
PubMed score by year
PubTator Score 6.35
PubTator score by year
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Related Publications
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PMID
Year
Title