Protein Summary
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
- ENST00000395952
- ENSP00000379282
- ENSG00000204427
- ENST00000440843
- ENSP00000410347
- ENST00000446529
- ENSP00000395665
- ENSG00000206403
- ENST00000548592
- ENSP00000448431
- ENST00000549722
- ENSP00000447549
- ENSG00000230475
- ENST00000549853
- ENSP00000447846
- ENSG00000236063
- ENST00000550556
- ENSP00000447498
- ENSG00000235676
- ENST00000551038
- ENSP00000449579
- ENSG00000231488
- ENST00000552042
- ENSP00000448451
- ENSG00000224552
- BAT5
- G5
- NG26
- BAT5
- NG26
- PP199
- D6S82E
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 0.87 | ||
transcription factor perturbation | 0.68 | ||
transcription factor | 0.63 | ||
phenotype | 0.61 | ||
tissue sample | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.3 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 89 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.3 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 89 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 3
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 1